论坛 › 《实况足球2013》 › 【3DM下载站/网盘分流】《实况足球2013（PES 2013）》PC版DEMO EPT汉化补丁及免安装简体中文硬盘版[CN]

T_i_a_n_y_- 发表于 2022-11-2 15:39

啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊啊

tracy1103 发表于 2022-11-5 15:43

顶顶顶顶顶顶顶顶顶顶顶顶

鱼挠白白 发表于 2022-11-5 18:55

shishikan

cristiano77770 发表于 2022-11-5 20:26

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qzuserac 发表于 2022-11-8 21:36

根目录

sickinziyu 发表于 2022-11-9 13:09

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Tz-Shmily 发表于 2022-11-10 10:48

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法特14 发表于 2022-11-10 13:33

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chenyong1982 发表于 2022-11-11 17:10

SD FGDDFSFGSFGDS

3234764690 发表于 2022-11-15 23:08

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qq307296747 发表于 2022-11-17 10:31

这应该是最接近于平替实况8的了吧

浪漫海阔天空 发表于 2022-11-17 16:23

谢谢分享

人生旅途 发表于 2022-11-18 21:26

DFRGDGDFGFDGDF

chenyuan2046 发表于 2022-11-18 23:24

感谢分享啊啊

linjinwei777 发表于 2022-11-19 11:25

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5王海 发表于 2022-11-19 13:59

不错宣传册

太阳出来喽 发表于 2022-11-19 16:14

下载下载，谢谢谢谢

77234025a 发表于 2022-11-21 11:35

顶顶顶顶顶顶顶顶

hutpk1 发表于 2022-11-21 16:36

看看好不好玩

zk19891010 发表于 2022-11-21 20:31

好东西   谢谢

yjj198481 发表于 2022-11-21 23:39

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renzhesband 发表于 2022-11-22 00:53

Osteoarthritis is one of the most prevalent chronic diseases. Cartilage inflammation in osteoarthritis results from pain in articular joints. Anti-inflammatory drugs provide relief by hindering the production of pro-inflammatory cytokines and interleukin-6. Targeted delivery of anti-inflammatory drugs is very effective in the treatment of osteoarthritis. This approach reduces the usage of therapeutic drug dosages and unwanted side effects. Here, we fabricated a non-invasive and efficient targeted drug delivery system to reduce persistent inflammation in an osteoarthritis model. Temperature-sensitive hollow dextran/poly(N-isopropyl acrylamide) nanoparticles were synthesized by the destruction of N,N'-bis(acryloyl)cystamine crosslinked cores in imidazolium-based ionic liquids. The copolymerized 2-acrylamido-2-methylpropane sulfonic acid created sulfur functionalities that increase the loading of therapeutic KAFAK peptides. The chemical structure of the polymer nanoparticles was analyzed with UV-Visible, Fourier transform infrared, and X-ray photoelectron spectroscopy. The thermal responsive characteristics of the nanoparticles were determined with dynamic light scattering, scanning electron microscopy, and transmission electron microscopy analyses. Moreover, the synthesized nanoparticles were used as drug carriers to reduce inflammation in an Ex Vivo osteoarthritis model. The KAFAK-loaded hollow dextran/PNIPAM nanoparticles effectively delivered therapeutic peptides in cartilage explants to suppress inflammation. These thermoresponsive nanoparticles could be an effective drug delivery system to deliver anti-inflammatory therapeutic peptides in a highly osteoarthritic environment.

dech12109 发表于 2022-11-22 22:08

9999999999999999999

chen4444 发表于 2022-11-22 22:09

挖坟了，下载玩一下

wanyouxi233 发表于 2022-11-22 23:12

RE: 【3DM下载站/网盘分流】《实况足球2013（PES 2013）》PC版DEMO EPT汉化补丁及免安装简体中文硬盘版 [修改]

3dm_18609802 发表于 2022-11-24 00:39

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我爱我家35 发表于 2022-11-24 00:54

感谢楼主，分享

chuiniubideo 发表于 2022-11-24 01:48

擦拭擦擦是

jickcap 发表于 2022-11-24 15:35

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hello460 发表于 2022-11-24 16:21

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